特定健診対象者における歯周疾患スクリーニングテストとメタボリックシンドロームとの関連性  [in Japanese] Relationship between Screening Test for Periodontal Disease and Metabolic Syndrome among Participants in Specific Health Checkups  [in Japanese]

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Author(s)

    • 岩崎 正則 IWASAKI Masanori
    • 新潟大学大学院医歯学総合研究科口腔健康科学講座予防歯科学分野 Division of Preventive Dentistry, Department of Oral Health Science, Graduate School of Medical and Dental Sciences, Niigata University
    • 葭原 明弘 YOSHIHARA Akihiro
    • 新潟大学大学院医歯学総合研究科口腔健康科学講座予防歯科学分野 Division of Preventive Dentistry, Department of Oral Health Science, Graduate School of Medical and Dental Sciences, Niigata University
    • 宮崎 秀夫 MIYAZAKI Hideo
    • 新潟大学大学院医歯学総合研究科口腔健康科学講座予防歯科学分野 Division of Preventive Dentistry, Department of Oral Health Science, Graduate School of Medical and Dental Sciences, Niigata University

Abstract

本研究の目的は特定健診対象者における歯周疾患スクリーニングテストとメタボリックシンドロームの関連を検討することである.2009,2010年度に本調査に参加した40〜74歳,488名を本研究対象とした.唾液中の潜血反応を利用した歯周疾患スクリーニングテストを行い,対象者を陽性群,陰性群に分けた.また特定健診の結果からメタボリックシンドローム判定項目である肥満,高血圧,高血糖,および脂質異常を定義した.さらに肥満者でかつ判定項目3つ(高血圧,高血糖,脂質異常)のうち2つ以上を持つ者をメタボリックシンドロームと定義した.年齢,性別,および喫煙状況を共変量としたロジスティック回帰モデルを用い,歯周疾患スクリーニングテストとメタボリックシンドロームの関連を評価した.歯周疾患スクリーニングテスト陰性群を基準としたとき,陽性群の肥満,およびメタボリックシンドロームに対する調整オッズ比はそれぞれ1.64(95%信頼区間=1.03-2.61)および2.49(95%信頼区間=1.34-4.63)であり,統計学的に有意だった.歯周疾患スクリーニングテスト結果と高血圧,高血糖,および脂質異常の間には統計学的に有意な関連は認められなかった.本研究結果から,特定健診対象者において歯周疾患スクリーニングテストとメタボリックシンドロームの間には有意な関連があることが示された.

The aim of this study was to investigate the association between a screening test for periodontal disease and metabolic syndrome-related factors among participants in specific health checkups. The study involved 488 subjects (male: 190, female: 298) aged 40-74 years who participated in specific health checkups conducted in Joetsu City, Japan in 2009 and 2010. Screening for periodontal disease was performed using the saliva occult blood test, and the subjects were divided into two groups, screen-positive and screen-negative. From the results of health checkups, the subjects were defined as obese (male: waist circumference ≥85cm, female: waist circumference ≥90cm), with high blood pressure (systolic blood pressure ≥130mm Hg, diastolic blood pressure ≥85mm Hg or use of medication for hypertension), high blood glucose (hemoglobin Alc ≥5.2% or use of medication for hyperglycemia), and lipid abnormality (triglycerides ≥1.5mg/mL, HDL-cholesterol<0.4mg/mL, or use of medication for lipid abnormality). Furthermore, metabolic syndrome was defined as obese subjects with ≥2 of 3 metabolic syndrome components (high blood pressure, high blood glucose, and lipid abnormality). Logistic regression was employed to evaluate the relationships between the screening test for periodontal disease and metabolic syndrome components using age, gender, and the current smoking status as covariates. A total of 204 subjects (41.8%) were classified as screen-negative and 284 (58.2%) as screen-positive. Using the screen-negative group as a referent group, the adjusted odds ratios (95% confidence interval) for obesity and metabolic syndrome of the screen-positive group were calculated to be 1.64 (1.03-2.61) and 2.49 (1.34-4.63) respectively, being considered significant. No significant relationships were observed between the results of the screening test for periodontal disease and high blood pressure, high blood glucose, and lipid abnormality. The study results suggest a significant relationship between the screening test for periodontal disease and metabolic syndrome among participants in specific health checkups.

Journal

  • JOURNAL OF DENTAL HEALTH

    JOURNAL OF DENTAL HEALTH 61(5), 573-580, 2011

    Japanese Society for Oral Health

References:  18

Codes

  • NII Article ID (NAID)
    110008761935
  • NII NACSIS-CAT ID (NCID)
    AN00081407
  • Text Lang
    JPN
  • Article Type
    ART
  • ISSN
    0023-2831
  • NDL Article ID
    023229160
  • NDL Call No.
    Z19-144
  • Data Source
    CJP  NDL  NII-ELS  J-STAGE 
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