牡丹皮の研究-3-牡丹皮の抗炎症作用-1- Studies on MOUTAN CORTEX (III) : On Anti-inflammatory Activities (Part 1)

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抄録

In traditional Chinese medicine, "Mudanpi" (Paeonia moutan SIM., root cortex) is one of the most important crude drugs, and is used particularly for the treatment of female genital inflammatory diseases. In this work, the anti-inflammatory effects of 70% MeOH extract of "Mudanpi" and of various fractions derived therefrom were examined. The 70% MeOH extract inhibited the arthritis induced by Freund's complete adjuvant in rat, and the glyco-sidic fraction containing no paeonol which is a major component of "Mudanpi", inhibited blood platelet agglutination, and showed anti-plasminogen and anti-plasmin activities. The fact that "Mudanpi" significantly inhibited autoimmune and/or allergic inflammation is in good accord with the clinical applications of "Mudanpi" practised in traditional Chinese medicine.

収録刊行物

  • 生薬学雑誌

    生薬学雑誌 33(3), p178-184, 1979-09

    日本生薬学会

各種コード

  • NII論文ID(NAID)
    110008907881
  • NII書誌ID(NCID)
    AN00116895
  • 本文言語コード
    JPN
  • ISSN
    00374377
  • NDL 記事登録ID
    2094954
  • NDL 刊行物分類
    SD0(薬学)
  • NDL 雑誌分類
    ZS51(科学技術--薬学)
  • NDL 請求記号
    Z19-375
  • データ提供元
    NDL  NII-ELS  NDL-Digital 
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