牡丹皮の研究-8-抗血栓形成作用について-2- Studies on Moutan Cortex VIII : Inhibitory Effects on the Intravascular Coagulation (Part 2)
Seventy percent methanol extract (M) from Moutan Cortex (root cortex of Paeonia moutan Sim., Paeoniaceae) was investigated from an anatomical or pathological view point for its effect on endotoxin-induced experimental disseminated intravascular coagulation (DIC) in normal and hyperlipemia rats. M inhibited the endotoxin-induced hemorrhagic necrosis in liver and fibrin thrombi in renal glomeruli in normal rats. It also prevented the endotoxin-induced hepatic vein thrombosis in hyperlipemia rats.
生薬学雑誌 38(4), p307-312, 1984-12