生薬および関連植物の抗コクシジウム活性成分の探索-1-アジサイからのcisならびにtrans-febrifugineの単離および抗コクシジウム活性について Studies on Anticoccidial Constituents of Crude Drugs and Related Plants (I) : Isolation and Biological Activities of cis-and trans-febrifugine from Hydrangea macrophylla

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抄録

Twentythree crude drugs and related plants were examined for their anticoccidial activity by the use of the experimental coccidiosis in chicken. The activity was found in the dry leaves and calyxes of some Hydrangea plants. As the active components of H. macrophylla subsp. macrophylla forma macrophylla, febrifugines were isolated which have been known to be contained in Dichroa febrifuga and H. umbellata. However, although the febrifugines in the latter two plants were reported to be mainly trans, in the H. macrophylla plants, cis-febrifugine was found to be a major component and the trans-counterpart, a minor component. Furthermore, the cis-isomer showed no anticoccidial activity in chicken even at the concentration level of 25 times the effective dose (3 ppm, IE=100) of the trans-isomer.

収録刊行物

  • 生薬学雑誌

    生薬学雑誌 44(4), p288-292, 1990-12

    日本生薬学会

被引用文献:  2件中 1-2件 を表示

各種コード

  • NII論文ID(NAID)
    110008908259
  • NII書誌ID(NCID)
    AN00116895
  • 本文言語コード
    JPN
  • 資料種別
    雑誌論文
  • ISSN
    00374377
  • NDL 記事登録ID
    3711184
  • NDL 刊行物分類
    SD0(薬学)
  • NDL 雑誌分類
    ZS51(科学技術--薬学)
  • NDL 請求記号
    Z19-375
  • データ提供元
    CJP引用  NDL  NII-ELS  NDL-Digital 
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