Studies on Chinese Medicinal Herbs Increasing the Rate of Orthodontic Tooth Movement
We examined nine Chinese medicinal herbs, Salvia miltiorrhiza (Dan-shen), Ligusticum chuanxiong (Chuan-xiong), Achyranthes bidentata (Niu.xi), Hosta plantaginea (Yu-zan), Hosta yentricosa (Zhi-yu-zan), Drynaria fortunei (Gu-shui-bu), Ophiopogon japonicus (Mai-men-dong), Clematis chinensis (Wei-lin-xian), Lycopodium clavatum (Shen-jin-cao) for their effects on orthodontic tooth movement in guinea-pigs and rabbits. Some drugs increased the rate of orthodontic tooth movement. Hosta ventricosa increased the rate of movement by 2.11 times, and Salvia miltiorrhizan, Ligusticum chuanxiong and Achyranthes bidentata by 1.6 times. Histological observations showed that the bone resorption on the pressure side of moving tooth was more obvious in those treated animals than in control animals. Besides, Hosta ventricosa and Drynaria fortunei invigorated the osteoblasts and caused more bone deposition on the tension side of moving tooth.
生薬学雑誌 46(2), p131-135, 1992-06