小児副腎皮質癌の1例 [in Japanese] A pediatric case of adrenocortical carcinoma [in Japanese]
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Adrenocortical carcinoma is a rare malignant disease with a poor prognosis that occurs at a rate of 0.3 per 1 million children per year. Since the development of adrenocortical carcinoma in children commonly involves hormonal functional tumors, it is essential to assess informative symptoms, such as virilization and Cushing syndrome. Complete surgical resection is crucial for obtaining a better prognosis, and systemic chemotherapy and mitotane therapy are also important treatment options. We herein report a case of adrenocortical carcinoma with multiple lung metastases in a 2-year-old male with an approximately one year history of virilization and Cushing syndrome. Because the tumor was inoperable and resistant to both chemotherapy and mitotane therapy, the patient died twelve months after the initiation of first chemotherapy.
- Akita journal of medicine
Akita journal of medicine 39(3・4), 139-143, 2012