A Study on the Usefulness of Bofu-tsusho-san in Treating Obesity-related Sleep Apnea Syndrome (SAS)

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著者

    • Oba Asami
    • Department of Gerontechnology, Research Institute, National Center for Geriatrics and Gerontology
    • Oba Toshihiko
    • Department of Gerontechnology, Research Institute, National Center for Geriatrics and Gerontology
    • Matsuura Hiroyuki
    • Department of Gerontechnology, Research Institute, National Center for Geriatrics and Gerontology
    • Suzuki Satoshi
    • Department of Respiratory Medicine, Graduate School of Medicine, University of Tokyo
    • Ino Takeshi
    • Doctoral program of Medical Science, Kitasato University graduate school

抄録

Obesity is an important complicating factor in Sleep Apnea Syndrome (SAS), and correction of obesity is a factor that must always be taken into account in the treatment of SAS. In this study, Bofu-tsusho-san - a Kampo preparation indicated for the treatment of obesity - was administered to obese SAS patients for a duration of eight weeks, and its usefulness was tested. To all patients, Continuous Positive Airway Pressure (CPAP) therapy, the standard treatment for SAS was provided. For this reason, the Apnea Hypopnea Index (AHI) was kept to a mild level or below, and changes were not observed in the approximate administration of Bofu-tsusho-san. Significant changes in Body Mass Index (BMI), neck girth and abdominal girth, were not observed, either. However, ESS scores were observed decreasing over time, with a significant difference after eight weeks of administration. Furthermore, in terms of subjective symptoms, constipation improved significantly after eight weeks of administration, and it was observed that appetite scores also decreased. Based on these findings, it appears that Bofu-tsusho-san, through combined use with CPAP therapy, is useful in limiting progression of obesity -a complicating factor in SAS - and improving SAS's subjective symptoms.

収録刊行物

  • Kawasaki journal of medical welfare

    Kawasaki journal of medical welfare 18(2), 29-36, 2013

    川崎医療福祉大学

各種コード

  • NII論文ID(NAID)
    110009587141
  • NII書誌ID(NCID)
    AA11108172
  • 本文言語コード
    ENG
  • ISSN
    13415077
  • データ提供元
    NII-ELS 
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