polyHEMA/TMPTハイドロゲルによる cetylpyridinium chloride の長期徐放 : 担持機序とリチャージ条件の検討

• 北川 晴朗

  阪大院・歯・保存

• 今里 聡

  阪大院・歯・理工

• 竹田 かほる

  阪大院・歯・保存

• 北川 蘭奈

  阪大院・歯・保存

• 三木 彩希

  阪大院・歯・保存

• 林 美加子

  阪大院・歯・保存

書誌事項

タイトル別名

• Long-term release of cetylpyridinium chloride by polyHEMA/TMPT hydrogel : loading mechanism and release profile under different recharging protocol

抄録

As a new approach to achieve long-lasting antibacterial effects for reconstructive materials, we have developed polyHEMA/TMPT hydrogel particles loaded with cetylpyridinium chloride (CPC), that can release and recharge CPC. Previously, we found that the hydrogel comprising 50% HEMA/50% TMPT was suitable for release of CPC, and the recharging CPC to this particle possible. Here we analyzed the CPC-loading mechanism of polyHEMA/TMPT hydrogel and release profile under different recharging protocol. CPC was found to be loaded in the micellized state, and continuous release was obtained by usage of high concentrations of CPC with short-period recharging.

収録刊行物

• 日本歯科理工学会誌 = The journal of the Japanese Society for Dental Materials and Devices

  日本歯科理工学会誌 = The journal of the Japanese Society for Dental Materials and Devices 32 (2), 122-, 2013-03-25

  一般社団法人日本歯科理工学会

詳細情報

• CRID: 1570854177927400960
• NII論文ID: 110009596421
• NII書誌ID: AA12452694
• ISSN: 18844421
• Web Site: https://search.jamas.or.jp/link/ui/2014043109
• 本文言語コード: ja
• データソース種別:
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