EVALUATION OF AIRWAY NARROWING BY MOSTGRAPH AND SPIROMETRY : EXAMINATION USING A REVERSIBILITY TEST

• Shibasaki Atsushi

  Shibasaki Clinic

• Kurosawa Hajime

  Center for Environmental Conservation and Research Safety, Tohoku University:Department of Occupational Health, Tohoku University School of Medicine

• Tamura Gen

  Airway Institute in Sendai, CO. Ltd.

Bibliographic Information

Other Title

• モストグラフとスパイロメトリーによる気道狭窄の評価 : 可逆性試験を用いた検討
• モストグラフ ト スパイロメトリー ニ ヨル キドウ キョウサク ノ ヒョウカ : カギャクセイ シケン オ モチイタ ケントウ

Abstract

Background and objective: MostGraph is an apparatus for measuring respiratory resistance and respiratory reactance, using the forced oscillation technique. Because these parameters are measured during tidal breathing of subjects, measuring technique is easy with little burden on subjects. In the present study, we conducted spirometry and MostGraph at the same time and examined the clinical significance of parameters of MostGraph. Methods: Subjects were 52 out-patients who underwent a reversibility test. Spirometry and MostGraph are simultaneously practiced both before and after short acting β_2 agonist (SABA) inhalation. Results: Between each parameter of both methods before SABA inhalation, we confirmed significant correlations between many indexes of both manners. Above all, the strongest correlation was found between Fres and FEV_1. In relationships between the percent changes of each parameter of both techniques by SABA inhalation, we also found a significant correlation between percent change of Fres and that of FEV_1. In addition, there was a hyperbolic relation between change in Fres and that in FEV_1 by SABA inhalation. Conclusion: We confirmed not only that airway narrowing itself significantly correlates with Fres, but also that elastic resistance of respiratory system changes in association with change of airway narrowing. Thus, our findings suggest that the percent change of Fres may provide a diagnostic criterion for a reversibility test in all parameters of MostGraph.

Journal

• Japanese Journal of Allergology

  Japanese Journal of Allergology 62 (5), 566-573, 2013

  Japanese Society of Allergology

Keywords

• MostGraph
• reversibility
• spirometry
• the forced oscillation technique
• the fraction of exhaled nitric oxide

Details

• CRID: 1390282679976581632
• NII Article ID: 110009612555
• NII Book ID: AN00012583
• DOI: 10.15036/arerugi.62.566
• ISSN: 13477935
• ISSN: 00214884
• NDL BIB ID: 024687464
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I024687464
• Web Site: https://search.jamas.or.jp/link/ui/2013284180
• Text Lang: ja
• Data Source:
  • JaLC
  • NDL
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed