前立腺がん発症率に対するビタミンE摂取の影響 : その無作為化比較試験のメタ分析による評価  [in Japanese] Effect of vitamin E intake on prostate cancer incidence : Its evaluation by meta-analysis of randomized controlled trials  [in Japanese]

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Author(s)

Abstract

Prostate cancer is one of the most increasing prevalence of cancers in Japan. It is well known that vitamin E acts as a useful chemo-preventive agent against several types of cancers. However there are conflicting results on a role of vitamin E in the prevention of prostate cancer. In this study, a meta-analysis of current evidence from randomized controlled trials (RCTs) was conducted to evaluate the role of vitamin E in the prevention of prostate cancer. Relevant articles in PubMed were systematically searched for RCTs of vitamin E intake and incidence of prostate cancer. From 455 potential articles, 6 eligible RCTs articles were selected. Meta-analysis of 6 RCTs identified showed no significant difference on the effect of vitamin E intake alone on the reduction in incidence of prostate cancer (Relative Risk (RR)=0.88, 95% Confidential Interval (CI): 0.71, 1.08, P=0.22; random effects). However, there was heterogeneity in this meta-analysis, so that this result suggested that vitamin E intake might have a protective effect against prostate cancer in some cases.

Journal

  • VITAMINS

    VITAMINS 87(7), 359-363, 2013

    THE VITAMIN SOCIETY OF JAPAN

References:  13

Codes

  • NII Article ID (NAID)
    110009624884
  • NII NACSIS-CAT ID (NCID)
    AN00207833
  • Text Lang
    JPN
  • Article Type
    NOT
  • ISSN
    0006-386X
  • NDL Article ID
    024786576
  • NDL Call No.
    Z19-36
  • Data Source
    CJP  NDL  NII-ELS  J-STAGE 
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