J0210202 Dynamic Optical Coherence Straingraphyを用いたOA軟骨診断法の基礎的検討([J021-02]診療技術と臨床バイオメカニクスセッション(2))

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  • J0210202 Fundamental study of OA cartilage diagnosis using the Dynamic Optical Coherence Straingraphy

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Many of the elderly are predisposed to develop osteoarthritis (OA), although it is quite difficult to diagnose the early-grade OA even by latest imaging modalities. In this study, we have proposed Dynamic OCSA (Optical Coherence Straingraphy), which is a tomographically micro-visualizing method of visco-elastic properties estimated from continuous OCT images. This is based on the speckle tracking algorithm, which is composed mainly of the recursive cross-correlation and the sub-pixel analysis, e.g. upwind gradient method and image deformation method. These are applied continuously to the synthetic OCT images, then can provide temporal and spatial distribution of not only deformation velocity but also strain rate. This was experimentally applied to comparatively both normal cartilages and cartilages degenerated by the collagenase enzyme treatment. Consequently, the strain rate was observed to be spatially localized within the superficial tangential zone. Additionally, the attenuation of time-varying strain rate was visualized to be lager in the superficial zone than that in the middle zone. There appeared to be the significant increase in attenuation with increasing the treatment time. It is, therefore, possible to diagnose the degeneration of the early-grade OA, taking the attenuation of relaxation modulus into consideration.

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  • 年次大会

    年次大会 2014 (0), _J0210202--_J0210202-, 2014

    一般社団法人 日本機械学会

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