0313 脂質殻ナノ気泡の分子シミュレーション

• 越山 顕一朗

  阪大

• 和田 成生

  阪大

書誌事項

タイトル別名

• 0313 Molecular Dynamics Simulations of Lipid Coated Nanobubble

抄録

We investigate the collapsing mechanisms of a lipid coated nanobubble and the subsequent lipid vesicle formation by coarse grained molecular dynamics (CGMD) simulations. A preformed nanobubble coated by lipid monolayer in water is a model of an aqueous dispersion of phospholipids under negative pressure in sonication. Relaxing to a positive pressure, the spherical bubble shape deforms into irregular prolate ellipsoidal shape and the monolayer starts to fold from an apsis of the ellipsoid. The local folding is rapidly propagated in the ellipsoid, pushing gas core, and a discoidal membrane forms. The discoidal membrane develops into a unilamellar vesicle via bowl shape.

収録刊行物

• 流体工学部門講演会講演論文集

  流体工学部門講演会講演論文集 2015 (0), _0313-1_-_0313-2_, 2015

  一般社団法人 日本機械学会

キーワード

• DPPC
• MARTINI
• Drug Delivery System
• Sonoporation
• Gyration Tensor

詳細情報

• CRID: 1390282680859250304
• NII論文ID: 110010047097
• DOI: 10.1299/jsmefed.2015._0313-1_
• ISSN: 24242896
• Web Site: https://www.jstage.jst.go.jp/article/jsmefed/2015/0/2015__0313-1_/_pdf
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可