1H45 ヒツジ膝前十字靭帯再建術後の自家アキレス腱の力学的特性評価に関する研究  [in Japanese] 1H45 Investigation of mechanical properties of Achilles' tendon autograft after ovine anterior cruciate ligament reconstruction  [in Japanese]

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Author(s)

    • 井桝 浩貴 IMASU Hiroki
    • 早稲田大学先端生命医科学センターTWIns Department of Modern Mechanical Engineering, Waseda University
    • 伊藤 匡史 ITO Masafumi
    • 東京女子医科大学病院整形外科 Department of Orthopedic Surgery, Tokyo Women's Medical University Hospital
    • 高野 和也 TAKANO Kazuya
    • 早稲田大学先端生命医科学センターTWIns Department of Modern Mechanical Engineering, Waseda University
    • 奥田 慶也 OKUDA Noriya
    • 早稲田大学先端生命医科学センターTWIns Department of Modern Mechanical Engineering, Waseda University
    • 梅津 光生 UMEZU Mitsuo
    • 早稲田大学先端生命医科学センターTWIns Cooperative Major in Advanced Biomedical Sciences, Waseda University

Abstract

We aimed to investigate mechanical properties of Achilles' tendon autograft after ovine anterior cruciate ligament reconstruction. Mature three female ovine were used in this study. In each ovine, the right knee underwent anterior cruciate ligament reconstruction. They were sacrificed at 13 weeks after surgery. In each ovine, both the knees were harvested, and the left knee was used to obtain the data of the native anterior cruciate ligament. Drawer test for stability evaluation and tensile test for evaluation of mechanical properties were performed. The knee was mounted on a jig with 5 degrees of freedom for tensile testing, four cycles of anterior-posterior shear loads (50 N) were applied to the knee at 30°, 60° and 90° of the flexion with a cross head speed set at 20 mm/min. The displacement of the femur relative to tibia was defined as the anterior-posterior translation of the knee. (1) Stress relaxation test (5 N, 10 min), (2) cyclic load test (0-50 N, 10 cycles, 10 mm/min), and (3) tensile test (300 mm/min) were performed in turn. Before each testing, tissue cross-sectional area was measured with the device using a laser displacement sensor. At 13 weeks after the implantation, the anterior-posterior translation of the reconstructed knee was greater than native anterior cruciate ligament. Ultimate strength and maximum Young's modulus of the femur-graft-tibia complex were smaller than native anterior cruciate ligament. These testing methods presented here is effective to gain insight into in vivo biomechanical remodeling of reconstructed tissues.

Journal

  • The Proceedings of the Bioengineering Conference Annual Meeting of BED/JSME

    The Proceedings of the Bioengineering Conference Annual Meeting of BED/JSME 2016.28(0), _1H45-1_-_1H45-5_, 2016

    The Japan Society of Mechanical Engineers

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