Voltage-gated potassium channel antibodies associated limbic encephalitis in a patient with invasive thymoma

• Ohshita, Tomohiko

• Kawakami, Hideshi

• Maruyama, Hirofumi

• Kohriyama, Tatsuo

• Arimura, Kimiyoshi

• Matsumoto, Masayasu

抄録

Recently, limbic encephalitis (LE) associated with Voltage-gated potassium channel antibody (VGKC-Ab) has been postulated as a new autoimmune disorder. Most previously reported cases of VGKC-Ab-associated LE were non-paraneoplastic, and reports of a paraneoplastic type are rare. Here we describe a 59-year-old woman with paraneoplastic VGKC-Ab-associated LE preceding the recurrence of invasive thymoma. There was a close temporal relationship between the clinical course and the changes of the VGKC-Ab titer. Unlike many of the non-paraneoplastic VGKC-Ab-associated LE cases, our cases showed the more extensive high intensity lesions on MRI and the absence of seizure and hyponatremia.

収録刊行物

• Journal of the Neurological Sciences

  Journal of the Neurological Sciences 250 (1-2), 167-169, 2006-12-01

  Elsevier

キーワード

• Invasive thymoma
• Limbic encephalitis
• Voltage-gated potassium channel antibody

詳細情報

• CRID: 1050014791011221504
• NII論文ID: 120000878108
• NII書誌ID: AA00703265
• Web Site: http://ir.lib.hiroshima-u.ac.jp/00017102
• 本文言語コード: en
• 資料種別: journal article
• データソース種別:
  • IRDB
  • CiNii Articles