Inter- and Intramolecular Additions of 1-Alkenylboronic Acids or Esters to Aldehydes and Ketones Catalyzed by Rhodium(I) Complexes in Basic, Aqueous Solutions

• Takezawa, Akinori

• Yamaguchi, Kenji

• Ohmura, Toshimichi

• Yamamoto, Yasunori

• Miyaura, Norio

Abstract

Grignard-type addition reaction of 1-alkenylboronic acids or their esters to aldehydes or ketones were carried out in aqueous MeOH or DME in the presence of KOH (1 equivalent) and an RhCl(dppf) or Rh(OH)(dppf) catalyst (3 mol%). The utility of the protocol was demonstrated in the corresponding intramolecular reaction giving cyclic homoallylic alcohols.

Journal

• Synlett

  Synlett 2002 (10), 1733-1735, 2002-10

  Georg Thieme Verlag

Keywords

• alkenylboron
• rhodium
• catalyst
• addition

Details

• CRID: 1050564288932585344
• NII Article ID: 120000954917
• ISSN: 14372096
• ISSN: 09365214
• HANDLE: 2115/14622
• Text Lang: en
• Article Type: journal article
• Data Source:
  • IRDB
  • CiNii Articles