A Palladium-Catalyzed Biaryl Coupling of Arylboronic Acids in Aqueous Media Using A Gluconamide-Substituted Triphenylphosphine (GLCAphos) Ligand

• Ueda, Masato

• Nishimura, Masato

• Miyaura, Norio

Abstract

A water-soluble phosphine ligand, N-(4-diphenyl-phosphino)phenylmethyl gluconamide (GLCAphos), was newly synthesized to perform the palladium-catalyzed biaryl coupling of arylboronic acids in a single aqueous media. The catalyst prepared from GLCAphos revealed higher activity than that synthesized from Ph2P(m-C6H4SO3Na) or P(m-C6H4SO3Na)3 for various haloarenes.

Journal

• Synlett

  Synlett 2000 (6), 0856-0858, 2000-06

  Georg Thieme Verlag

Keywords

• cross-coupling
• palladium
• biaryl
• aqueous media
• water-soluble ligand

Details

• CRID: 1050282813955874816
• NII Article ID: 120000956139
• ISSN: 14372096
• ISSN: 09365214
• HANDLE: 2115/14623
• Text Lang: en
• Article Type: journal article
• Data Source:
  • IRDB
  • CiNii Articles