Medical procedures and risk for sporadic creutzfeldt-jakob disease, Japan, 1999-2008
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To elucidate the association between medical procedures and sporadic Creutzfeldt-Jakob disease (sCJD), we analyzed medical procedures (any surgical procedure, neu- rosurgery, ophthalmic surgery, and blood transfusion) for patients registered by the CJD Surveillance Committee in Japan during 1999-2008. We conducted an age-stratified case-control study with 753 sCJD patients and 210 controls and a study of patients who underwent neurosurgical or ophthalmic surgical procedures at the same hospital. Although the control group was relatively small, no evidence was found that prion disease was transmitted through the investigated medical procedures before onset of sCJD. After onset of sCJD, 4.5% of the sCJD patients underwent operations, including neurosurgical for 0.8% and ophthalmic for 1.9%; no special precautions against transmission of prion diseases were taken. Fortunately, we have not identified patients with prion disease attributed to these operations. Our findings indicate that surgical procedures or blood transfusion had little effect on the incidence of sCJD.
金沢大学医薬保健研究域医学系
収録刊行物
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- Emerging Infectious Diseases
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Emerging Infectious Diseases 15 (2), 265-271, 2009-02-01
National Center for Infectious Diseases
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詳細情報 詳細情報について
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- CRID
- 1050282810924895360
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- NII論文ID
- 120002104596
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- NII書誌ID
- AA11211604
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- ISSN
- 10806040
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- HANDLE
- 2297/24042
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- 本文言語コード
- en
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- 資料種別
- journal article
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- データソース種別
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- IRDB
- CiNii Articles