Second malignant neoplasms after treatment for osteosarcoma: a report of three cases.

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<p>We report second malignant neoplasms which developed between 7 and 19 years after treatment in 3 pediatric patients with osteosarcoma. Two patients had been treated with only surgery, and another patient had been treated with a combination of surgery with chemotherapy and radiation therapy for primary lesions. Pediatric patients with osteosarcoma, in particular, require careful long-term follow-up to monitor not only metastases but also development of second malignant neoplasms.</p>

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  • Acta Medica Okayama

    Acta Medica Okayama 47 (2), 129-133, 1993-04

    Okayama University Medical School

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