An efficient procedure for preparation of 2-monoalkyl or 2-monoaryl-3-ethoxycyclobutanones

• Matsuo, Jun-ichi

• Okuno, Ryosuke

• Takeuchi, Kosuke

• Kawano, Mizuki

• Ishibashi, Hiroyuki

抄録

Optimized reaction conditions for the preparation of various 2-monosubstituted 3-ethoxycyclobutanones are described. 2-Monoalkyl 3-ethoxycyclobutanones were efficiently prepared by the reaction of the corresponding carboxylic acid chlorides and an excess amount of ethyl vinyl ether in the presence of diisopropylethylamine at 90 °C in a sealed tube. 2-Monoaryl 3-ethoxycyclobutanones were prepared by using 2,6-lutidine as a base in the above-mentioned procedure. © 2010 Published by Elsevier Ltd. All rights reserved.

金沢大学医薬保健研究域薬学系

収録刊行物

• Tetrahedron Letters

  Tetrahedron Letters 51 (29), 3736-3737, 2010-07-21

  Elsevier

詳細情報

• CRID: 1050564285907483264
• NII論文ID: 120002314577
• NII論文ID: 120002224334
• NII書誌ID: AA00861801
• ISSN: 00404039
• HANDLE: 2297/24795
• Web Site: https://kanazawa-u.repo.nii.ac.jp/records/15296
• Web Site: http://hdl.handle.net/2297/24569
• 本文言語コード: en
• 資料種別: journal article
• データソース種別:
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  • CiNii Articles