Noncultured autologous adipose-derived stem cells therapy for chronic radiation injury.

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Abstract

Increasing concern on chronic radiation injuries should be treated properly for life-saving improvement of wound management and quality of life. Recently, regenerative surgical modalities should be attempted with the use of noncultured autologous adipose-derived stem cells (ADSCs) with temporal artificial dermis impregnated and sprayed with local angiogenic factor such as basic fibroblast growth factor, and secondary reconstruction can be a candidate for demarcation and saving the donor morbidity. Autologous adipose-derived stem cells, together with angiogenic and mitogenic factor of basic fibroblast growth factor and an artificial dermis, were applied over the excised irradiated skin defect and tested for Patients who were uneventfully healed with minimal donor-site morbidity, which lasts more than 1.5 years.

Journal

  • Stem Cells International

    Stem Cells International (2010), 532704, 2010

    Hindawi Publishing

Codes

  • NII Article ID (NAID)
    120003307671
  • Text Lang
    ENG
  • Article Type
    journal article
  • ISSN
    1687-9678
  • Data Source
    IR 
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