Quantitative screening of EGF receptor-binding peptides by using a peptide library with multiple fluorescent amino acids as fluorescent tags

• Kitamatsu, Mizuki

• Yamamoto, Takahiro

• Futami, Midori

• Sisido, Masahiko

Abstract

EGF receptor-binding peptides could be found by a peptide screening method using fifteen fluorescent amino acids as fluorescent tags. Of 225 peptides, we found an 8-mer peptide containing a dipeptide unit, Y-F, which was the strongest binding peptide to the EGF receptor.

Journal

• Bioorganic & Medicinal Chemistry Letters

  Bioorganic & Medicinal Chemistry Letters 20 (20), 5976-5978, 2010-10-15

  Pergamon-Elsevier Science Ltd.

Keywords

• Peptide
• Peptide library
• Peptide screening
• EGFR
• Fluorescent amino acid

Details

• CRID: 1050002212335695232
• NII Article ID: 120003386547
• NII Book ID: AA1079577X
• ISSN: 0960894X
• Web Site: https://ousar.lib.okayama-u.ac.jp/46939
• Text Lang: en
• Article Type: journal article
• Data Source:
  • IRDB
  • CiNii Articles