SR-PSOX/CXCL16 plays a critical role in the progression of colonic inflammation.

• Uza, Norimitsu

• Nakase, Hiroshi

• Yamamoto, Shuji

• Yoshino, Takuya

• Takeda, Yasuhiro

• Ueno, Satoru

• Inoue, Satoko

• Mikami, Sakae

• Matsuura, Minoru

• Shimaoka, Takeshi

• Kume, Noriaki

• Minami, Manabu

• Yonehara, Shin

• Ikeuchi, Hiroki

• Chiba, Tsutomu

Abstract

Inflammatory bowel disease (IBD) is initiated and perpetuated by a dysregulated immune response to unknown environmental antigens such as luminal bacteria in genetically susceptible hosts. SR-PSOX/CXCL16, a scavenger receptor that binds phosphatidylserine and oxidised lipoprotein, has both phagocytic activity and chemotactic properties. The aim of this study was to investigate the role of SR-PSOX/CXCL16 in patients with IBD and experimental murine colitis.

Journal

• Gut

  Gut 60 (11), 1494-1505, 2011-11

  BMJ Publishing Group

Details

• CRID: 1050001335723575296
• NII Article ID: 120003497105
• NII Book ID: AA12306353
• ISSN: 14683288
• HANDLE: 2433/149206
• Text Lang: en
• Article Type: journal article
• Data Source:
  • IRDB
  • CiNii Articles