Piezoelectric materials mimic the function of the cochlear sensory epithelium.
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Cochlear hair cells convert sound vibration into electrical potential, and loss of these cells diminishes auditory function. In response to mechanical stimuli, piezoelectric materials generate electricity, suggesting that they could be used in place of hair cells to create an artificial cochlear epithelium. Here, we report that a piezoelectric membrane generated electrical potentials in response to sound stimuli that were able to induce auditory brainstem responses in deafened guinea pigs, indicating its capacity to mimic basilar membrane function. In addition, sound stimuli were transmitted through the external auditory canal to a piezoelectric membrane implanted in the cochlea, inducing it to vibrate. The application of sound to the middle ear ossicle induced voltage output from the implanted piezoelectric membrane. These findings establish the fundamental principles for the development of hearing devices using piezoelectric materials, although there are many problems to be overcome before practical application.
収録刊行物
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- Proceedings of the National Academy of Sciences of the United States of America
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Proceedings of the National Academy of Sciences of the United States of America 108 (45), 18390-18395, 2011-11-08
National Academy of Sciences
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詳細情報 詳細情報について
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- CRID
- 1050001335723702528
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- NII論文ID
- 20000855545
- 120003644363
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- NII書誌ID
- AA00786025
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- ISSN
- 00278424
- 10916490
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- HANDLE
- 2433/151840
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- 本文言語コード
- en
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- 資料種別
- journal article
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- データソース種別
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