High-speed atomic force microscopy coming of age High-speed atomic force microscopy coming of age

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Abstract

High-speed atomic force microscopy (HS-AFM) is now materialized. It allows direct visualization of dynamic structural changes and dynamic processes of functioning biological molecules in physiological solutions, at high spatiotemporal resolution. Dynamic molecular events unselectively appear in detail in an AFM movie, facilitating our understanding of how biological molecules operate to function. This review describes a historical overview of technical development towards HS-AFM, summarizes elementary devices and techniques used in the current HS-AFM, and then highlights recent imaging studies. Finally, future challenges of HS-AFM studies are briefly discussed. © 2012 IOP Publishing Ltd.

Journal

  • Nanotechnology

    Nanotechnology 23(6), 62001, 2012-02-17

    Institute of Physics

Cited by:  1

Codes

  • NII Article ID (NAID)
    120003989064
  • NII NACSIS-CAT ID (NCID)
    AA10863359
  • Text Lang
    ENG
  • Article Type
    Journal Article
  • ISSN
    0957-4484
  • Data Source
    CJPref  IR 
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