もやもや病診断における頸動脈管径測定の有用性に関する検討 Narrowed Petrous Carotid Canal Detection for the Early Diagnosis of Moyamoya Disease

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Abstract

目的:もやもや病は幼少期から内頸動脈終末部が進行性に狭窄する.もやもや病症例では頸動脈管が健常者と比較して,より低形成となることが考えられる.本後向き研究では頭部CT検査で頸動脈管径を測定することによるもやもや病早期診断の可能性につき検討した.対象と方法:25例のもやもや病症例群(男性15例,女性20例,年齢:6-71歳,平均26.1歳)と明らかな頭蓋内病変を認めない性別と年齢を一致させ,頭部CT検査を受けた症例を対照群とした.頭部CT検査で両群の頸動脈管最大径を測定し,両群間を比較検討した.結果:もやもや病症例群の頸動脈管最大径(平均4.70 ± 0.61mm)は対照群(平均5.62 ±0.61mm,p < 0.01)と比較して有意な狭小化が示された.考察:頭部単純CT検査で頸動脈管径を評価することにより,もやもや病の早期検出をできる可能性があると考えられた.結論:もやもや病早期診断における頸動脈管径測定の有用性が示唆された.

Purpose : Patients with moyamoya disease (MMD) exhibit narrowed internal carotid arteries (ICAs) because the distal ends of the bilateral ICAs have become progressively stenosed, starting mainly in childhood. Accordingly, the petrous carotid canals in MMD patients are suspected to be more hypoplastic than those in control subjects. In this study, the diagnostic value of conventional computed tomography for MMD patients was retrospectively evaluated by comparing the caliber of the bilateral carotid canals in MMD patients with that in control subjects. Materials and methods : Thirty-five patients with MMD (15 males, 20 females; age range/average age : 6-71 / 26.1 years old) and age- and sex-matched control subjects underwent conventional head computed tomography. The maximal petrous carotid canal diameters of the two groups were measured and compared. Results : The maximal petrous carotid canal diameter was significantly smaller in the moyamoya patients (mean ±standard deviation[mm] = 4.70 ± 0.61) than in the control subjects (5.62 ± 0.61,p < 0.01). Conclusion : Conventional head computed tomography revealed narrowed petrous carotid canals in the MMD patients. This basic information could be utilized to screen patients who will require further examination, especially among those with underlying MMD.

Journal

  • 福岡医学雑誌

    福岡医学雑誌 103(10), 206-214, 2012-10-25

    福岡医学会

Codes

  • NII Article ID (NAID)
    120004929974
  • NII NACSIS-CAT ID (NCID)
    AN00215478
  • Text Lang
    ENG
  • Article Type
    journal article
  • Journal Type
    大学紀要
  • ISSN
    0016-254X
  • NDL Article ID
    024263878
  • NDL Call No.
    Z19-86
  • Data Source
    NDL  IR 
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