MOLECULAR MARKERS OF PERITONEAL DISSEMINATION IN GASTRIC CANCER

• Fujii, Kiyomu

• Kuniyasu, Hiroki

抄録

type:Article

Peritoneal dissemination is a special condition of gastric cancer metastasis, which worsens the quality of patients' lives and is often difficult to control. In this study, we describe the basic features of the peritoneal dissemination of gastric cancer. Some molecular events are associated with the peritoneal dissemination, including c-met gene amplification, chromosome 7q deletion, and Reg Ⅳ overexpression. Especially, Reg Ⅳ overexpression enhances the antiapoptotic property of gastric cancer cells. In contrast, activation of PPARg inhibits the peritoneal dissemination by the pro-apoptotic effect.

identifier:Journal of Nara Medical Association Vol.62 No.6 p.95-107

identifier:13450069

identifier:http://ginmu.naramed-u.ac.jp/dspace/handle/10564/2295

identifier:Journal of Nara Medical Association, 62(6): 95-107

収録刊行物

• Journal of Nara Medical Association

  Journal of Nara Medical Association 62 (6), 95-107, 2011-12-31

  奈良医学会

キーワード

• 腫瘍マーカー
• 胃腫瘍
• 腫瘍播種
• c-met癌原遺伝子蛋白質
• 染色体欠失
• PPAR Gamma

詳細情報

• CRID: 1050845762425371904
• NII論文ID: 120004973964
• NII書誌ID: AA11252383
• ISSN: 13450069
• Web Site: http://hdl.handle.net/10564/2295
• Web Site: https://search.jamas.or.jp/link/ui/2012161693
• 本文言語コード: en
• 資料種別: departmental bulletin paper
• データソース種別:
  • IRDB
  • CiNii Articles