Peptide and peptidomimetic ligands for CXC chemokine receptor 4 (CXCR4).

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Abstract

The development of novel peptide and peptidomimetic ligands for the CXC chemokine receptor 4 (CXCR4) as therapeutic agents for HIV-1 infection, cancer, and immune system diseases has grown over the last decade. In this perspective article, the design of CXCR4 agonists and antagonists from endogenous stromal cell-derived factor-1 (SDF-1)/CXCL12 and horseshoe crab-derived antimicrobial peptides and their therapeutic and diagnostic applications are described.

Journal

  • Organic & biomolecular chemistry

    Organic & biomolecular chemistry 10(30), 5720-5731, 2012-03-19

    Royal Society of Chemistry

Codes

  • NII Article ID (NAID)
    120005243444
  • NII NACSIS-CAT ID (NCID)
    AA1168650X
  • Text Lang
    ENG
  • Article Type
    journal article
  • ISSN
    1477-0520
  • Data Source
    IR 
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