Molecular machines directly observed by high-speed atomic force microscopy

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Abstract

Molecular machines made of proteins are highly dynamic and carry out sophisticated biological functions. The direct and dynamic high-resolution visualization of molecular machines in action is considered to be the most straightforward approach to understanding how they function but this has long been infeasible until recently. High-speed atomic force microscopy has recently been realized, making such visualization possible. The captured images of myosin V, F1-ATPase, and bacteriorhodopsin have enabled their dynamic processes and structure dynamics to be revealed in great detail, giving unique and deep insights into their functional mechanisms. © 2013 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.

Journal

  • FEBS Letters

    FEBS Letters 587(3), 997-1007, 2013-04-17

    Federation of European Biochemical Societies / Elsevier

Codes

  • NII Article ID (NAID)
    120005304730
  • NII NACSIS-CAT ID (NCID)
    AA00642943
  • Text Lang
    ENG
  • Article Type
    journal article
  • ISSN
    0014-5793
  • Data Source
    IR 
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