Human intestinal spirochetosis is significantly associated with sessile serrated adenomas/polyps
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Abstract
It remains unclear whether or not human intestinal spirochetosis (HIS) has any associated symptoms or lesions. In this study, we assessed the prevalence of HIS in sessile serrated adenomas/polyps (SSA/Ps) and their possible association. Following identification of early cecal cancer with SSA/P accompanied by a colonization of HIS, we went on to conduct a retrospective case-control study using endoscopically resected SSA/P specimens to examine the frequency of HIS infection in SSA/Ps. Nineteen SSA/P cases and 172 controls were obtained. The rate of HIS infection was significantly higher at 52.6% (10/19) in the SSA/P cases compared to the controls at 8.1% (14/172). Our SSA/P series were associated with a remarkably higher rate of HIS than controls or than previously reported. This is the first report to provide evidence for potential association between HIS and SSA/Ps. (C) 2014 Elsevier GmbH. All rights reserved.
Journal
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- Pathology, Research and Practice
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Pathology, Research and Practice 210 (7), 440-443, 2014-07
Elsevier
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Details 詳細情報について
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- CRID
- 1050564288970261120
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- NII Article ID
- 120005462415
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- NII Book ID
- AA00769966
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- HANDLE
- 2115/56700
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- ISSN
- 03440338
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- Text Lang
- en
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- Article Type
- journal article
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- Data Source
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- IRDB
- CiNii Articles