Extraction of astatine isotopes for development of radiopharmaceuticals using a 211Rn–211At generator

• Maeda E.

• Yokoyama Akihiko

• Taniguchi T.

• Washiyama K.

• Nishinaka Ichiro

• 横山 明彦

Abstract

In order to utilize a 211At isotope, a promising α-emitter for radionuclide therapy, the chemical properties of astatine isotopes are studied. We have examined wet chemistry methods through the distribution ratios of astatine in liquid–liquid extraction. The astatine isotopes have been found to be well extracted into DIPE and MIBK. We observed that the distribution ratio of astatine isotopes increases with concentrations of HCl greater than 3 M, while it decreases with the HCl concentration less than 2 M. The results will be useful for development of the 211Rn–211At generator.

In Press

Journal

• Journal of Radioanalytical and Nuclear Chemistry

  Journal of Radioanalytical and Nuclear Chemistry 303 (2), 1465-1468, 2014-01-01

  Kluwer Academic Publishers

Keywords

• 211Rn–211At generator
• Astatine
• Liquid–liquid extraction
• Radionuclide therapy

Details

• CRID: 1390576282608194688
• NII Article ID: 120005516436
• NII Book ID: AA10523088
• ISSN: 02365731
• DOI: 10.24517/00010771
• DOI: 10.24517/00010746
• Web Site: http://hdl.handle.net/2297/40157
• Web Site: http://hdl.handle.net/2297/41328
• Text Lang: en
• Data Source:
  • JaLC
  • IRDB
  • CiNii Articles