RIG-I-like receptors: cytoplasmic sensors for non-self RNA.

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Abstract

Viral infection results in the generation of non-self RNA species in the cells, which is recognized by retinoic acid inducible gene-I-like receptors (RLRs), and initiates innate antiviral responses, including the production of proinflammatory cytokines and type I interferon. In this review, we summarize reports on virus-specificity of RLRs, structures of non-self RNA patterns, structural biology of RLRs, and the signaling adapter molecules involved in antiviral innate immunity.

Journal

  • Immunological reviews

    Immunological reviews 243(1), 91-98, 2011-08-26

    wiley

Codes

  • NII Article ID (NAID)
    120005587805
  • NII NACSIS-CAT ID (NCID)
    AA00670246
  • Text Lang
    ENG
  • Article Type
    journal article
  • ISSN
    0105-2896
  • Data Source
    IR 
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