Variation of Cell Spreading on Titanium Dioxide Film by Periodic Nanostructures Formation with Femtosecond Laser

• Shinonaga Togo

• Tsukamoto Masahiro

• Peng Chen

• Hanawa Takao

• Nagai Akiko

抄録

Coating of titanium dioxides (TiO2) film on Ti plate has been conducted to improve biocompatibility of Ti. We have developed coating techniques of the film on Ti plate with an aerosol beam. Controlling cell spreading by periodic structure formation on biomaterials was also a useful method for improving the biocompatibility. In our previous study, the periodic nanostructures were formed on the film by femtosecond laser irradiation at a fundamental wave length (775 nm). Period of the nanostructures was about 230 nm. Cell tests shows cell spreading along the grooves of the nanostructures although it was not done for the film without the nanostructures. Then, influence of the periods of the nanostructures on cell spreading has not been investigated yet. The periods can be varied by changing the laser wavelength. In this study, the nanostructures with the periods of 130 and 230 nm were produced on the film by using the femtosecond laser at the wavelengths of 388 and 775 nm. After a cell test, cell spreading along the grooves of the nanostructures with the periods of 130 amd 230 nm was observed. These results suggested that cell spreading was controlled by using the nanostructures with the periods of 130 and 230 nm.

収録刊行物

• Transactions of JWRI

  Transactions of JWRI 43 (2), 7-10, 2014-12

  大阪大学接合科学研究所

キーワード

• Femtosecond Laser
• Titanium dioxide
• Aerosol beam
• Periodic nanostructures
• Cell test

詳細情報

• CRID: 1390857202732302464
• NII論文ID: 120005588201
• NII書誌ID: AA00867058
• DOI: 10.18910/51363
• HANDLE: 11094/51363
• ISSN: 03874508
• 本文言語コード: en
• データソース種別:
  • JaLC
  • IRDB
  • CiNii Articles