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Abstract

Subcutaneous fat depots play an important role in regulating metabolic profile in Japanese postmenopausal women. We investigated the possibility of neck circumference (NC) as a surrogate marker for metabolic disease risk estimates in Japanese postmenopausal women. We examined the association of NC with several markers of insulin resistance, lipid metabolism and atherosclerosis in 64 healthy postmenopausal women aged 63.6 ± 7.1 years in community-based samples in Japan. As a result, NC was significantly associated with indices of whole body obesity and visceral fat accumulation, such as body mass index (BMI) and waist circumference (WC). In the analysis of biomarkers for insulin resistance, NC was positively correlated to HbA1c, homeostasis model assessment ratio (HOMA-R) and leptin. In addition, an increase in triglycerides (TG) and a decrease in HDL-cholesterol (HDL-C) were also associated with NC. Interestingly, NC was also associated with atherosclerosis-related indices. The measurement of NC is an easy, inexpensive and reproducible method for assessment of obesity, and a possible predictor to identify the risk for future metabolic diseases in Japanese postmenopausal women.

Journal

  • Hiroshima Journal of Medical Sciences

    Hiroshima Journal of Medical Sciences 63(4), 27-32, 2014-12

    Hiroshima University Medical Press

Codes

  • NII Article ID (NAID)
    120005601180
  • NII NACSIS-CAT ID (NCID)
    AA00664312
  • Text Lang
    ENG
  • Article Type
    departmental bulletin paper
  • ISSN
    0018-2052
  • Data Source
    IR 
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