Adjuvant Chemotherapy for Patients with Soft Tissue Sarcoma

• Ozaki, Toshifumi

• Sugihara, Shinsuke

• Hamada, Masanori

• Nakagawa, Yukou

• Inoue, Hajime

抄録

Forty patients with soft tissue sarcoma (Enneking's stage I and II) were treated in our department between 1965 and 1992. We administered VACA regimen (composed of vincristine, actinomycin-D, cyclophosphamide, and doxorubicin) to 14 of 40 patients. Among 40 patients, the 5-year survival rate was 56% in 14 patients with chemotherapy and 39% in 26 without chemotherapy (p<0.02). In 32 patients of Stage II, the 5-year survival rate was 40% in 11 patients with chemotherapy and 31 % without chemotherapy (p<0.05). The improvement of the survival rate was due to delay in the development of lung metastases (chemotherapy group: 21.2 months after first visit, non-chemotherapy group: 9.4 months) and prolongation of the survival period after metastases (chemotherapy group: 26 months, non-chemotherapy group: 7.4 months).

収録刊行物

• Hiroshima Journal of Medical Sciences

  Hiroshima Journal of Medical Sciences 42 (3), 109-115, 1993-09

  Hiroshima University Medical Press

キーワード

• Soft tissue sarcoma
• Chemotherapy
• Survival

詳細情報

• CRID: 1050296265985376000
• NII論文ID: 120005625700
• NII書誌ID: AA00664312
• Web Site: http://ir.lib.hiroshima-u.ac.jp/00037923
• 本文言語コード: en
• 資料種別: departmental bulletin paper
• データソース種別:
  • IRDB
  • CiNii Articles