Catalytic asymmetric synthesis of the pentacyclic core of (-)-nakadomarin A via oxazolidine as an iminium cation equivalent.

• Tsuji, Nobuya

• Stadler, Michael

• Kazumi, Naoya

• Inokuma, Tsubasa

• 小林, 祐輔

• 竹本, 佳司

抄録

A facile and catalytic asymmetric synthesis of the pentacyclic core of (-)-nakadomarin A, containing all the stereogenic centers of the natural product was achieved. The key intermediate involves the oxazolidine moiety as an iminium cation equivalent. An efficient method for the removal of the N-hydroxyethyl group is also described.

収録刊行物

• Organic & biomolecular chemistry

  Organic & biomolecular chemistry 12 (40), 7919-7922, 2014-08-27

  Royal Society of Chemistry

キーワード

• Carbolines/chemical synthesis
• Carbolines/chemistry
• Catalysis
• Cations/chemistry
• Imines/chemistry
• Molecular Conformation
• Organometallic Compounds/chemistry
• Oxazoles/chemistry
• Palladium/chemistry
• Stereoisomerism

詳細情報

• CRID: 1050564285769596544
• NII論文ID: 120005657914
• NII書誌ID: AA1168650X
• ISSN: 14770520
• HANDLE: 2433/200199
• 本文言語コード: en
• 資料種別: journal article
• データソース種別:
  • IRDB
  • CiNii Articles