Ni-Catalyzed Synthesis of Fluoroarenes via [2+2+2] Cycloaddition Involving α-Fluorine Elimination

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Abstract

A method for direct synthesis of tetrasubstituted fluoroarenes via nickel-catalyzed [2+2+2] cycloaddition is presented. The reaction combines one molecule of 1,1-difluoroethylene with two molecules of alkynes and involves sequential cleavage of the C[BOND]F and C[BOND]H bonds in difluoroethylene. The catalytic cycle is established by reduction of the intermediary NiII fluoride with a triethylborane-based borate.

Journal

  • Chemistry : a European journal

    Chemistry : a European journal 21(38), 13225-13228, 2015-09

    WILEY-VCH

Keywords

Codes

  • NII Article ID (NAID)
    120005669427
  • NII NACSIS-CAT ID (NCID)
    AA11076269
  • Text Lang
    ENG
  • Article Type
    journal article
  • ISSN
    0947-6539
  • Data Source
    IR 
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