ネパールにおける遺伝性ヘモグロビンE(HbE)の解析  [in Japanese] Analysis of hereditary hemoglobin E (HbE) in Nepal  [in Japanese]

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Abstract

It has been suggested that a high frequency of abnormal hemoglobin might reflect an advantage due to a reduced susceptibility to malaria. To evaluate this malaria hypothesis, we analyzed abnormal hemoglobin in two neighboring populations of Nepal: the Danuwar and the Tamang. It was hypothesized that the settlements of the former were biologically adapted to the malarial environment, whereas those of the latter were customarily adapted. We detected nine heterozygotes for the β^E mutation generating HbE in four families in the Danuwar setllement by analysis of isoelectric focusing (IEF) and high performance liquid chromatography (HPLC).

Journal

  • Research bulletin of Kyushu Junior College of Kinki University

    Research bulletin of Kyushu Junior College of Kinki University (34), 67-74, 2004

    近畿大学九州短期大学

Keywords

Codes

  • NII Article ID (NAID)
    120005737635
  • NII NACSIS-CAT ID (NCID)
    AN10297606
  • Text Lang
    JPN
  • Article Type
    departmental bulletin paper
  • Journal Type
    大学紀要
  • ISSN
    09164383
  • NDL Article ID
    7257035
  • NDL Source Classification
    ZE16(社会・労働--家事・家政--学術誌)
  • NDL Call No.
    Z6-1401
  • Data Source
    NDL  IR 
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