Multi-institutional retrospective study for the evaluation of ocular function-preservation rates in maxillary sinus squamous cell carcinomas with orbital invasion

• Sakashita, Tomohiro

• Hayashi, Ryuichi

• Homma, Akihiro

• Matsuura, Kazuto

• Kato, Kengo

• Kawabata, Kazuyoshi

• Monden, Nobuya

• Hasegawa, Yasuhisa

• Onitsuka, Tetsuro

• Fujimoto, Yasushi

• Iwae, Shigemichi

• Okami, Kenji

• Matsuzuka, Takashi

• Yoshino, Kunitoshi

• Fujii, Masato

抄録

Background. This study aimed to evaluate ocular function and survival rates among treatment modalities in patients with maxillary sinus cancer with orbital invasion. Methods. Eighty-seven patients were classified according to the main treatment modality. Ocular function preservation rates and survival rates were evaluated for each therapeutic modality. Results. The 5-year overall survival rate for the en bloc resection, conservative surgery, superselective intra-arterial chemotherapy and radiotherapy (RADPLAT), intra-venous chemoradiotherapy (IV-CRT) was 70%, 35%, 49%, and 31%, respectively. Ocular function preservation rate for each group was 15%, 27%, 30%, and 17%, respectively. In the en bloc resection group, there was no significant difference in the 5-year overall survival rate between patients with orbital exenteration and those without orbital exenteration (72% vs 71%, p=0.9321). Conclusions. The en bloc resection group showed a favorable survival rate, but a low preservation rate. Preservation of orbital contents did not reduce the survival rate.

収録刊行物

• Head & Neck

  Head & Neck 37 (4), 537-542, 2015-04

  Wiley

キーワード

• maxillary sinus cancer
• orbital invasion
• ocular function
• squamous cell carcinoma
• chemoradiotherapy

詳細情報

• CRID: 1050001202673776256
• NII論文ID: 120005740326
• HANDLE: 2115/61134
• ISSN: 10433074
• 本文言語コード: en
• 資料種別: journal article
• データソース種別:
  • IRDB
  • CiNii Articles