A strategy for sequence control in vinyl polymers via iterative controlled radical cyclization.

• Hibi, Yusuke

• Ouchi, Makoto

• Sawamoto, Mitsuo

Abstract

There is a growing interest in sequence-controlled polymers toward advanced functional materials. However, control of side-chain order for vinyl polymers has been lacking feasibility in the field of polymer synthesis because of the inherent feature of chain-growth propagation. Here we show a general and versatile strategy to control sequence in vinyl polymers through iterative radical cyclization with orthogonally cleavable and renewable bonds. The proposed methodology employs a repetitive and iterative intramolecular cyclization via a radical intermediate in a one-time template with a radical-generating site at one end and an alkene end at the other, each of which is connected to a linker via independently cleavable and renewable bonds. The unique design specifically allowed control of radical addition reaction although inherent chain-growth intermediate (radical species) was used, as well as the iterative cycle and functionalization for resultant side chains, to lead to sequence-controlled vinyl polymers (or oligomers).

Journal

• Nature communications

  Nature communications 7 2016-03-21

  Nature Publishing Group

Keywords

• Chemical sciences
• Materials science
• Organic chemistry

Details

• CRID: 1050282810806693376
• NII Article ID: 120005743638
• ISSN: 20411723
• HANDLE: 2433/210191
• Text Lang: en
• Article Type: journal article
• Data Source:
  • IRDB
  • CiNii Articles