Influence of dioxin exposure upon levels of prostate-specific antigen and steroid hormones in Vietnamese men

• Sun, Xian Liang

• Kido, Teruhiko

• Honma, Seijiro

• Okamoto, Rie

• Manh, Ho Dung

• Maruzeni, Shoko

• Nishijo, Muneko

• Nakagawa, Hideaki

• Nakano, Takeshi

• Koh, Eitetsu

• Takasuga, Takumi

• Nhu, Dang Duc

• Hung, Nguyen Ngoc

• Son, Le Ke

抄録

Most studies on the relationship between Agent Orange and prostate cancer have focused on US veterans of the Vietnam War. There have been few studies focusing on the relationship between levels of prostate-specific antigen (PSA) and dioxins or steroid hormones in Vietnamese men. In 2009–2011, we collected blood samples from 97 men who had resided in a “dioxin hotspot” and 85 men from a non-sprayed region in Vietnam. Then levels of PSA, dioxins, and steroid hormones were analyzed. Levels of most dioxins, furans, and non-ortho polychlorinated biphenyls were higher in the hotspot than those in the non-sprayed region. Levels of testosterone, dehydroepiandrosterone, and estradiol differed significantly between the hotspot and the non-sprayed region, but there were no correlations between levels of PSA and steroid hormones and dioxins in either of the two regions. Our findings suggest that PSA levels in Vietnamese men are not associated with levels of dioxin or steroid hormones in these two regions. © 2016 Springer-Verlag Berlin Heidelberg

Embargo Period 12 months

収録刊行物

• Environmental Science and Pollution Research

  Environmental Science and Pollution Research 23 (8), 7807-7813, 2016-04-01

  Springer Verlag

キーワード

• Polychlorinated biphenyls
• Polychlorinated dibenzo-p-dioxins
• Polychlorinated dibenzofurans
• Prostate-specific antigen
• Steroid hormones
• Vietnamese men

詳細情報

• CRID: 1050845760881255168
• NII論文ID: 120005743919
• NII書誌ID: AA11079143
• ISSN: 09441344
• ISSN: 16147499
• DOI: 10.1007/s11356-015-5931-3
• Web Site: http://hdl.handle.net/2297/44884
• Web Site: http://link.springer.com/content/pdf/10.1007/s11356-015-5931-3.pdf
• Web Site: http://link.springer.com/article/10.1007/s11356-015-5931-3/fulltext.html
• Web Site: http://link.springer.com/content/pdf/10.1007/s11356-015-5931-3
• 本文言語コード: en
• 資料種別: journal article
• データソース種別:
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