Deep sequencing reveals as-yet-undiscovered small RNAs in Escherichia coli

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In Escherichia coli, approximately 100 regulatory small RNAs (sRNAs) have been identified experimentally and many more have been predicted by various methods. To provide a comprehensive overview of sRNAs, we analysed the low-molecular-weight RNAs (< 200 nt) of E. coli with deep sequencing, because the regulatory RNAs in bacteria are usually 50-200 nt in length.

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  • BMC Genomics

    BMC Genomics 12 (1), 1-15, 2011-08-24

    BioMed Central Ltd

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