Programmable protein-protein conjugation via DNA-based self-assembly

• Shimada, Josui

• Maruyama, Tatsuo

• Kitaoka, Momoko

• Yoshinaga, Hisao

• Nakano, Koji

• Kamiya, Noriho

• Goto, Masahiro

Abstract

Protein molecules were precisely arrayed on a designable DNA scaffold close to each other using a DNA aptamer. By adding a chemical cross-linker, the neighboring protein molecules were effectively and covalently cross-linked to each other without losing their activities.

Journal

• Chemical Communications

  Chemical Communications 48 (50), 6226-6228, 2012-06-25

  Royal Society of Chemistry

Keywords

• Materials Chemistry
• Metals and Alloys
• Surfaces, Coatings and Films
• General Chemistry
• Ceramics and Composites
• Electronic, Optical and Magnetic Materials
• Catalysis

Details

• CRID: 1050575520347480832
• NII Article ID: 120006318790
• DOI: 10.1039/c2cc30618b
• ISSN: 1364548X
• ISSN: 13597345
• HANDLE: 20.500.14094/90004041
• Web Site: http://pubs.rsc.org/en/content/articlepdf/2012/CC/C2CC30618B
• Text Lang: en
• Article Type: journal article
• Data Source:
  • IRDB
  • Crossref
  • CiNii Articles
  • KAKEN