Activity of teicoplanin, a new glycopeptide, against anaerobic bacteria

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  • Kato Naoki
    Institute of Anaerobic Bacteriology, Gifu University School of Medicine
  • Kato Haru
    Institute of Anaerobic Bacteriology, Gifu University School of Medicine
  • Tanaka Yasunori
    Institute of Anaerobic Bacteriology, Gifu University School of Medicine
  • Tanaka Kaori
    Institute of Anaerobic Bacteriology, Gifu University School of Medicine
  • Watanabe Kunitomo
    Institute of Anaerobic Bacteriology, Gifu University School of Medicine
  • Ueno Kazue
    Institute of Anaerobic Bacteriology, Gifu University School of Medicine

Bibliographic Information

Other Title
  • 新glycopeptide系抗菌薬Teicoplaninの嫌気性菌に対する抗菌力
  • 全学的教育基盤システムとしてのLMSの活用支援と普及過程モデルの分析(3) : 平成18年度～平成23年度のコース数からみた利用状況の推移
  • ゼンガクテキ キョウイク キバン システム ト シテ ノ LMS ノ カツヨウ シエン ト フキュウ カテイ モデル ノ ブンセキ(3)ヘイセイ 18ネンド~ヘイセイ 23ネンド ノ コーススウ カラ ミタ リヨウ ジョウキョウ ノ スイイ

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Abstract

The in vitro activity of teicoplanin (TEIC), a new glycopeptide, was studied in a variety of anaerobic bacteria. TEIC was more active than vancomycin (VCM) against gram-positive cocci including Peptostreptococcus spp., Clostridium spp., and Gardnerella vaginalis, a fastidious facultative anaerobe, and comparable to VCM against Mobiluncus spp. Among gram-negative rods, although TEIC had little activity against Bacteroides spp. including Bacteroides fragilis group organisms, this compound was active against Prevotella spp. that were not susceptible to VCM. In addition, TEIC was more active than VCM against Porphyromonas spp. TEIC had little activity against Lactobacillus spp., of a major member of the intestinal flora, as did VCM.

Journal

  • CHEMOTHERAPY

    CHEMOTHERAPY 41 (Supplement2), 56-61, 1993

    Japanese Society of Chemotherapy

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