肥満・糖尿病克服を目的とした脂肪細胞研究の実践と栄養学研究への展開

IR Web Site

Bibliographic Information

Other Title
  • キョウジュ シュウニン キネン コウエン ヒマン ・ トウニョウビョウ コクフク オ モクテキ ト シタ シボウ サイボウ ケンキュウ ノ ジッセン ト エイヨウガク ケンキュウ エ ノ テンカイ
  • The research of adipocyte biology for the survive from obesity and diabetes and its development into nutritional intervention
  • ヒマン トウニョウビョウ コクフク オ モクテキ トシタ シボウ サイボウ ケンキュウ ノ ジッセン ト エイヨウガク ケンキュウ エノ テンカイ

Search this article

Abstract

White adipose tissue（WAT）is the main storage site for excess energy as triacylglycerides within specialized lipid-laden mature adipocytes. The expansion of WAT during the development of obesity can occur through increases in cell number（adipocyte hyperplasia）and in cell size（adipocyte hypertrophy）. Adipocytes are derived from preadipocytes which can proliferate throughout life to increase WAT mass. In addition, adipocyte cell death observed within pathologically expanding adipose tissue is also one of the important factors that contribute to the pathophysiological consequences of obesity. The objective of this review is to discuss the precise contribution of adipocyte life cycle to the pathogenesis of obesity and obesity-related disease and to indicate substantial progress in our lab concerning our knowledge of bioactive components in functional foods and their links to obesity.

Journal

Keywords

Details 詳細情報について

Report a problem

Back to top