Comparison of MRI sequences in ideal fiducial maker-based radiotherapy for prostate cancer.

• Tanaka, Osamu

• Komeda, Hisao

• Hattori, Mitsuyoshi

• Hirose, Shigeki

• Yama, Eiichi

• Matsuo, Masayuki

抄録

Prostate contouring using CT alone is difficult. To overcome the uncertainty, CT/MRI registration using a fiducial marker is generally performed. However, visualization of the marker itself can be difficult with MRI. This study aimed to determine the optimal MRI pulse sequence for defining the marker as well as the prostate outline among five sequences.

A total of 21 consecutive patients with prostate cancer were enrolled. Two gold fiducial markers were placed before CT/MRI examination. We used the following five sequences: T1-weighted spin-echo (T1WI; TR/TE, 400-650/8ms); T2-weighted fast spin-echo (T2WI; 4000/80); T2*-2D-weighted gradient echo (T2*2D; 700/18); T2*-3D-weighted gradient echo (T2*3D; TR/TE1/deltaTE, 37/14/7.3); and contrast-enhanced T1-weighted spin-echo (CE-T1WI; 400-650/8). Qualitative image analysis of the sequences was performed by three observers. These observers subjectively scored all images on a scale of 1-3 (1=unclear, 2=moderate, 3=well visualized). A higher score indicated better visualization.

T2WI was significantly superior to the other sequences in terms of prostate definition. T2*2D and T2*3D were strongly superior to the other sequences and were significantly superior in terms of fiducial marker definition.

T2*2D and T2*3D are superior to the other sequences for prostate contouring and marker identification. Therefore, we recommend initial T2*3D and T2*2D examinations.

Prostate contouring using CT alone is difficult. To overcome the uncertainty, CT/MRI registration using a fiducial marker is generally performed. However, visualization of the marker itself can be difficult with MRI. This study aimed to determine the optimal MRI pulse sequence for defining the marker as well as the prostate outline among five sequences.

A total of 21 consecutive patients with prostate cancer were enrolled. Two gold fiducial markers were placed before CT/MRI examination. We used the following five sequences: T1-weighted spin-echo (T1WI; TR/TE, 400-650/8ms); T2-weighted fast spin-echo (T2WI; 4000/80); T2*-2D-weighted gradient echo (T2*2D; 700/18); T2*-3D-weighted gradient echo (T2*3D; TR/TE1/deltaTE, 37/14/7.3); and contrast-enhanced T1-weighted spin-echo (CE-T1WI; 400-650/8). Qualitative image analysis of the sequences was performed by three observers. These observers subjectively scored all images on a scale of 1-3 (1=unclear, 2=moderate, 3=well visualized). A higher score indicated better visualization.

T2WI was significantly superior to the other sequences in terms of prostate definition. T2*2D and T2*3D were strongly superior to the other sequences and were significantly superior in terms of fiducial marker definition.

T2*2D and T2*3D are superior to the other sequences for prostate contouring and marker identification. Therefore, we recommend initial T2*3D and T2*2D examinations.

収録刊行物

• Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology

  Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology 22 (6), 502-506, 2017-11

  VM Media SP. zo.o VM Group SK

キーワード

• Fiducial marker
• IMRT
• MRI
• Prostate cancer
• Registration

詳細情報

• CRID: 1050001338456696192
• NII論文ID: 120006381878
• ISSN: 15071367
• DOI: 10.1016/j.rpor.2017.10.002
• Web Site: https://asahi-u.repo.nii.ac.jp/records/9139
• Web Site: https://api.elsevier.com/content/article/PII:S1507136717300822?httpAccept=text/xml
• Web Site: https://api.elsevier.com/content/article/PII:S1507136717300822?httpAccept=text/plain
• 本文言語コード: en
• 資料種別: journal article
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