Characterization of two novel sialyl N-acetyllactosaminyl nucleotides separated from ovine colostrum

• Sasaki, Masashi

• Nakamura, Tadashi

• Hirayama, Kentaro

• Fukuda, Kenji

• Saito, Tadao

• Urashima, Tadasu

• Asakuma, Sadaki

Abstract

The milk/colostrum of some mammalian species is known to contain sugar nucleotides including uridine diphosphate (UDP) oligosaccharides in addition to lactose and milk oligosaccharides, but the detailed structures of these UDP oligosaccharides have not so far been clarified. In this study we isolated two UDP-sialyl N-acetyllactosamines from ovine colostrum and characterized them using H-1-NMR and MALDITOFMS spectroscopies. Their structures were found to be Neu5Gc(alpha 2 - 3) Gal (beta 1 - 4)GlcNAc alpha 1-UDP and Neu5Gc(alpha 2-6) Gal(beta 1-4)GlcNAc alpha 1-UDP.

Journal

• Glycoconjugate Journal

  Glycoconjugate Journal 33 (5), 789-796, 2016-10

  Springer

Keywords

• UDP sialyl N-acetyllactosamine
• UDP oligosaccharide
• Milk sugar nucleotide
• Ovine colostrum
• Milk oligosaccharide

Details

• CRID: 1050001337584037632
• NII Article ID: 120006390960
• NII Book ID: AA10451191
• ISSN: 02820080
• Web Site: https://obihiro.repo.nii.ac.jp/records/1223
• Text Lang: en
• Article Type: journal article
• Data Source:
  • IRDB
  • CiNii Articles