Lung Function in Individuals with and without Diabetes : Sex-and Age-Specific Analysis in a Large Population of Japanese Adults

• Sonoda Nao

• Morimoto Akiko

• Tatsumi Yukako

• Ohno Yuko

Bibliographic Information

Other Title

• 糖尿病者と非糖尿病者の肺機能の比較 : 大規模集団における性・年代別検討
• トウニョウビョウシャ　ト　ヒトウニョウビョウシャ　ノ　ハイキノウ　ノ　ヒカク　ダイキボ　シュウダン　ニ　オケル　セイ　ネンダイベツ　ケントウ

Abstract

Aim: This study was performed to assess lung function in individuals with and without diabetes in a large population of Japanese adults. Methods: This cross-sectional study included 15,516 participants aged 40–69 years who underwent a comprehensive medical check-up for the first time between April 2008 and March 2013 at Saku Central Hospital. Diabetes was defined by fasting plasma glucose ≥126 mg/dl, HbA1c ≥6.5%, or receiving medical treatment for diabetes. Lung function indices were the forced vital capacity (FVC) % predicted and forced expiratory volume in one second (FEV1) to FVC ratio (FEV1/FVC). Participants were stratified into sex and age categories (men aged 40–49, 50–59, and 60–69 years and women aged 40–49, 50–59, and 60–69 years). Differences in lung function between individuals with and without diabetes were determined by analysis of covariance. Results: In this study, 1,475 individuals were classified as having diabetes. In all categories, individuals with diabetes had a significantly lower FVC % predicted than those without diabetes after adjustment for age, height, waist circumference, smoking status (nonsmoker, ex-smoker, or current smoker), exercise habits (presence or absence), systolic blood pressure, high-density lipoprotein cholesterol, and log-transformed high-sensitivity C-reactive protein. In contrast, in all categories except women aged 40– 49 years, FEV1/FVC was not different between individuals with and without diabetes. Conclusion: Individuals with diabetes had a lower FVC % predicted than those without diabetes.

Journal

• 大阪大学看護学雑誌

  大阪大学看護学雑誌 24 (1), 1-9, 2018-03-31

  大阪大学大学院医学系研究科保健学専攻

Keywords

• 糖尿病
• 糖尿病合併症
• 肺機能
• diabetes
• complication
• lung function

Details

• CRID: 1390293810380811648
• NII Article ID: 120006407066
• NII Book ID: AN1048165X
• DOI: 10.18910/67816
• ISSN: 21898820
• HANDLE: 11094/67816
• Web Site: https://search.jamas.or.jp/link/ui/2018218729
• Text Lang: ja
• Data Source:
  • JaLC
  • IRDB
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Allowed