Follistatin-like 5 is expressed in restricted areas of the adult mouse brain: Implications for its function in the olfactory system Follistatin-like 5is expressed in restricted areas of the adult mouse brain: Implications for its function in the olfactory system:Fstl5 expression in the mouse brain

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Author(s)

Abstract

Follistatin‐like 5 (Fstl5), a member of the follistatin family of genes, encodes a secretory glycoprotein. Previous studies revealed that other members of this family including Fstl1 and Fstl3 play an essential role in development, homeostasis, and congenital disorders. However, the in vivo function of Fstl5 is poorly understood. To gain insight into the function of Fstl5 in the mouse central nervous system, we examined the Fstl5 expression pattern in the adult mouse brain. The results of in situ hybridization analysis showed a highly restricted pattern of Fstl5, namely, with localization in the olfactory system, hippocampal CA3 area and granular cell layer of the cerebellum. Restricted expression in the olfactory system suggests a possible role for Fstl5 in maintaining odor perception.

Journal

  • Congenital anomalies

    Congenital anomalies 54(1), 63-66, 2014-05

    Wiley

Codes

  • NII Article ID (NAID)
    120006457428
  • NII NACSIS-CAT ID (NCID)
    AA12100449
  • Text Lang
    ENG
  • Article Type
    journal article
  • ISSN
    0914-3505
  • Data Source
    IR  Crossref 
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