Facile Guanidine Formation under Mild Acidic Conditions

• Takeuchi, Kohei

• Nakayama, Atsushi

• Tanino, Keiji

• Namba, Kosuke

書誌事項

タイトル別名

• Facile Guanidine Formation under Mild Acidic Condition

抄録

An efficient method for converting isothioureas into guanidines was developed. The use of amine salts of bis(trifluoromethanesulfonyl)imide as a nitrogen source was found to induce an efficient conversion under weak acidic condition at 50 °C. The conversion was applicable to the various amines and carbamate-protected thioureas, and various carbamate-protected cyclic guanidines were obtained in high yields. In particular, ammonium bis(trifluoromethanesulfonyl)imide salt is a useful N1 source with which to construct mono-protected cyclic guanidines.

収録刊行物

• Synlett

  Synlett 27 (18), 2591-2596, 2016-08-01

  Thieme

キーワード

• guanidinylation
• cyclic guanidine
• isothiourea
• bis(trifluoromethansulfonyl)imide
• ammonium bis(trifluoromethansulfonyl)imidate

詳細情報

• CRID: 1050845762396583424
• NII論文ID: 120006485185
• NII書誌ID: AA10731110
• ISSN: 09365214
• ISSN: 14372096
• DOI: 10.1055/s-0035-1562478
• Web Site: https://repo.lib.tokushima-u.ac.jp/111876
• Web Site: http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0035-1562478.pdf
• 本文言語コード: en
• 資料種別: journal article
• データソース種別:
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  • CiNii Articles
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