Development of a traceable linker containing a thiol-responsive amino acid for the enrichment and selective labelling of target proteins
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A traceable linker that is potentially applicable to identification of a target protein of bioactive compounds was developed. It enabled not only thiol-induced cleavage of the linker for enrichment of the target protein but also selective labelling to pick out the target from contaminated non-target proteins for facile identification.
- Organic & Biomolecular Chemistry
Organic & Biomolecular Chemistry 12(23), 3821-3826, 2014-04-17
The Royal Society of Chemistry